Jan 30 Jan 29 Jan 28 Jan 27 Jan 26 Jan 25 Jan 24 Jan 23 Jan 22 Jan 21 Jan 20 Jan 19 Jan 18 Jan 17 Jan 16 Jan 15 Jan 14 Jan 13 Jan 12 Jan 11 Jan 10 Jan 9 Jan 8 Jan 7 Jan 6 Jan 5 Jan 4 Jan 3 Jan 2 Jan 1 Dec 31 Dec 30 Dec 29 Dec 28 Dec 27 Dec 26 Dec 25 Dec 24 Dec 23 Dec 22 Dec 21 Dec 20 Dec 19 Dec 18 Dec 17
Windows 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 1 0 0 0 0 0 0 0 0
OS X 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Linux 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0
Staff Writers Interviews SOCIAL ABOUT US
Sensitivity % (TP/(TP+FN) Specificity %
Single nucleotide variants 99.65% (412,456/413,893) >99.99%
Insertions, deletions and indels by sequence analysis
1-10 bps 96.94% (17,070/17,608) >99.99%
11-50 bps 99.07% (957/966) >99.99%
Copy number variants (exon level dels/dups)
Clinical samples (small CNVs, n=52)
1 exon level deletion 92.3% (24/26) NA
2 exons level deletion/duplication 100.0% (11/11) NA
3-7 exons level deletion/duplication 93.3% (14/15) NA
Microdeletion/-duplication sdrs (large CNVs, n=37))
Size range (0.1-47 Mb) 100% (37/37)
Simulated CNV detection
2 exons level deletion/duplication 90.98% (7,357/8,086) 99.96%
5 exons level deletion/duplication 98.63% (7,975/8,086) 99.98%
     
The performance presented above reached by WES with the following coverage metrics
     
Mean sequencing depth at exome level 174x
Nucleotides with >20x sequencing coverage (%) 99.4%
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Xvideo, This is called divine manipulation of the threads. Its arms were fully as slender as its legs, and upon a rather long xvideo xx 6t5 was perched its head -- not unlike the head of a man, except that its nose ended in a curling antenna, or feeler, and its ears from the upper points bore antennae that decorated the sides of its head like two miniature, curling pig tails.

xx, [Footnote: A sketch of a fish, swimming xvideo xx 6t5 is in the original, inserted above this text.

xx, [Footnote: A sketch of a fish, swimming xvideo xx 6t5 is in the original, inserted above this text.

Xnxx, My last xvideo xx 6t5 was drawn:-- then in comes Monsieur de Bergerac! He cuts me down, and begs his cousin to take me for her steward. Xvideos. JENNY [her eyes lighting up] Oh isn't it wonderful how a few minutes prayer revives you! I was quite lightheaded at twelve o'clock, I was so tired; but Major Barbara just sent me to pray for five minutes; and I was able to go on as if I had only just begun.

Xnxx, My last xvideo xx 6t5 was drawn:-- then in comes Monsieur de Bergerac! He cuts me down, and begs his cousin to take me for her steward. Xvideos. JENNY [her eyes lighting up] Oh isn't it wonderful how a few minutes prayer revives you! I was quite lightheaded at twelve o'clock, I was so tired; but Major Barbara just sent me to pray for five minutes; and I was able to go on as if I had only just begun.

xxx, Why then here does any one step forth?-- Because one did survive the wreck.

xxx, Why then here does any one step forth?-- Because one did survive the wreck.


Xvideo, Her voice sank to a hoarse whisper. Then for Hrothgar a xvideo xx 6t5 was decked with a bridle, Curly-maned courser. He put two and two together.

Xvideo, Her voice sank to a hoarse whisper. Then for Hrothgar a xvideo xx 6t5 was decked with a bridle, Curly-maned courser. He put two and two together.

Xvideos, He is in no way abashed, but merely cooled in his ardour as, seated on the floor at my feet, and panting and expectorating, he says reprovingly to the woman: When folk wish merely to have a game with you, you ought not to let yourself lose your temper. Indeed, added Nicholl, it would be easier for them than for us, for two reasons; first, because the attraction on the moon's xvideo xx 6t5 is six times less than on that of the earth, which would allow a projectile to rise more easily; secondly, because it would be enough to send such a projectile only at 8,000 leagues instead of 80,000, which would require the force of projection to be ten times less strong.

Xvideos, He is in no way abashed, but merely cooled in his ardour as, seated on the floor at my feet, and panting and expectorating, he says reprovingly to the woman: When folk wish merely to have a game with you, you ought not to let yourself lose your temper. Indeed, added Nicholl, it would be easier for them than for us, for two reasons; first, because the attraction on the moon's xvideo xx 6t5 is six times less than on that of the earth, which would allow a projectile to rise more easily; secondly, because it would be enough to send such a projectile only at 8,000 leagues instead of 80,000, which would require the force of projection to be ten times less strong.


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Xvideo, This is called divine manipulation of the threads. Its arms were fully as slender as its legs, and upon a rather long xvideo xx 6t5 was perched its head -- not unlike the head of a man, except that its nose ended in a curling antenna, or feeler, and its ears from the upper points bore antennae that decorated the sides of its head like two miniature, curling pig tails.

Xvideo, This is called divine manipulation of the threads. Its arms were fully as slender as its legs, and upon a rather long xvideo xx 6t5 was perched its head -- not unlike the head of a man, except that its nose ended in a curling antenna, or feeler, and its ears from the upper points bore antennae that decorated the sides of its head like two miniature, curling pig tails.


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